4. Further Nomenclature

About this Lecture

Lecture

In the fourth mini-lecture, we continue with learning about nomenclature of optical isomers by applying it to molecules in different orientations (Fischer projections), as well as applying Cahn-Ingold-Prelog’s system of R/S naming to a molecule with 8 different stereocentres, and how this gives hundreds of different stereoisomers.

Course

In this course, Professor David Bergbreiter (Texas A&M) introduces us to the concept of optical isomerism, the idea that certain molecules have mirror images of themselves which are non-superimposable, giving rise to a completely new set of properties. We begin by: (i) first looking at the concept of isomers, where optical isomers can be found and an initial concept of non-superimposability, then; (ii) talking about where optical isomers (or enantiomers) can be found in medicine and introducing optical activity; (iii) and then moving on to develop the idea of optical activity, and how we use that to name and identify different enantiomers, using various different examples; (iv) then briefly touching on other nomenclature and representations; (v) and finally using this new nomenclature we have learned on a more advanced level with real molecule.

Lecturer

Professor David Bergbreiter obtained his B.S from Michigan State and his PhD from MIT. He has worked as an academic in various places but he currently works at Texas A&M, receiving awards for his research and teaching at the university, including the South Eastern Conference Faculty Achievement Award (2017), the Regents' Professor Award (2016 – present), among many others. David Bergbreiter and his group explore new chemistry related to catalysis and polymer functionalization using the tools and precepts of synthetic organic chemistry to prepare functional oligomers or polymers that in turn are used to either affect catalysis in a greener, more environmentally benign way or to efficiently functionalize polymers. Often this involves developing new separation chemistry that creatively uses polymers but retains the reactivity of a low molecular weight catalyst, ligand, or reagent. These green chemistry projects involve fundamental research both in synthesis and catalysis but still have relevance to practical problems.