About the lecture

In this lecture, we think about the biological underpinnings of addiction, focusing in particular on: (i) the popular but reductionist view of dopamine as a ‘happy hormone’; (ii) the dopamine pathway, which originates in the ventral tegmental area and travels to the striatum; (iii) the nature of the dopamine pathway being conserved across different species; (iv) defining drugs as chemical substances which evoke a biological response in living organisms; (v) the commonality of all addictive drugs to act on the dopamine system by enhancing its activity; (vi) the receptors which nicotine, alcohol and opioids can each act on to release certain neurotransmitters.

About the lecturer

Dr Lauren Burgeno is a National Science Foundation Postdoctoral Fellow in the Department of Physiology, Anatomy and Genetics at the University of Oxford. Dr Burgeno’s research interests are in the mechanisms by which striatal acetylcholine gates cue-elicited dopamine release and how this contributes to addiction related behaviour. Some of Dr Burgeno’s recent publications include 'Time-dependent assessment of stimulus-evoked regional dopamine release' (2019) and 'Genetic isolation of hypothalamic neurons that regulate context-specific male social behaviour' (2016).